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Can rheumatoid arthritis increase cancer risk?

New Delhi: While the impact of rheumatoid arthritis on joint health is well documented, recent research has highlighted the possible link between rheumatoid arthritis and cancer, adding a new dimension to understanding the complex disease. Rheumatoid arthritis is a chronic autoimmune condition that primarily affects the joints, causing pain, swelling, stiffness, and potentially deformity over time.

It occurs when the immune system mistakenly attacks the body’s own tissues, primarily targeting the synovium, the lining of the joints. This chronic inflammation damages the joints and can lead to disability if left untreated.

Studies have shown that individuals with rheumatoid arthritis may have a slightly higher risk of certain types of cancer than the general population.

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“Although the exact reasons for this association are not fully understood, several factors are common risk factors such as chronic inflammation, immune disorders, smoking, obesity and genetic predisposition,” Dr. Vijay Ramanan, Senior Consultant Clinical Hematologist, Bone Marrow & Stem Cell Transplant, Ruby Hall Clinic, Pune told IANS.

Cancer types associated with rheumatoid arthritis include lymphoma, especially non-Hodgkin lymphoma, lung and skin cancer.

Compared with the general population, treated rheumatoid arthritis patients had a higher risk of all cancers and some site-specific cancers except breast, pancreas and endometrial cancer, according to a study recently published in The Lancet Regional Health. were less. general population.

Dr. Ramanan said that although the risk is relatively minor, proactive measures can help reduce it.

He suggested regular screening tests such as mammograms, Pap smears, colonoscopies and skin tests to detect cancer at an early, more treatable stage.

Adopting a healthy lifestyle, including a balanced diet, regular exercise, and avoiding tobacco use, can also help reduce the risk of cancer and improve overall health.

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